PA 800 plus Pharmaceutical Analysis System GenomeLab™ GeXP Genetic Analysis System
Protein Characterization Genetic Analysis
SDS-MW, IgG Purity & Heterogeneity Assay

Applications of CE SDS gel in development of biopharmaceutical antibody-based products (2008) R Rustandi, M Washabaugh, Y Wang. Electrophoresis, 29, p3612-3620.

A series of collaborations between various pharmaceutical companies and regulatory authorities concerning the analysis of biomolecules using capillary electrophoresis. (2006) B Nunnally et al. Chromatographia, 64 (5/6), p359-368.
Optimization and validation of a quantitative capillary electrophoresis sodium dodecyl sulfate method for quality control and stability monitoring of monoclonal antibodies. (2006) O Salas-Solano, B Tomlinson, S Du, M Parker, A Strahan, and S Ma. Analytical Chemistry, 78(18), p6583-94.
A microplate assay for the screening of ADAMTS-4 inhibitors. (2006) M Thomas, M Sabatini, F Bensaude, B Mignard, J-C ortuno, I Caron, J A Boutin, and G Ferry. Matrix Biology 25, p261-267.

Carbohydrate Labeling and Analysis
Antigen-specific human polyclonal antibodies from hyperimmunized cattle (2009) Y Kuroiwa, P Kasinathan, T Sathiyaseelan, J Jiao, H Matsushita, J Sathiyaseelan, H Wu, J Mellquist, M Hammitt, J Koster, S Kamoda, K Tachibana, I Ishida & J Robl. Nature Biotechnology 27, (2), p173-181.
Evaluation of glycosylation for quality assurance of antibody pharmaceuticals by capillary electrophoresis (2008) S Kamoda and K Kakehi. Electrophoresis, 29, p3595-3604.
Separation-based Glycoprofiling Approaches using Fluorescent Labels (2007) P Domann, A Pardos-Pardos, D L Fernandes, D Spencer, C Radcliffe, L Royle, R Dwek and P Rudd. Practical Proteomics, p70-75.
Site Specific N-Glycan Characterization of Human Complement Factor H. (2007) Francois Fenaille, Maxime Le Mignon, Catherine Groseil, Christine Ramon, Sandrine Riande, Laurent Siret, Nicolas Bihoreau. Glycobiology 17 (9), p932-944.
Capillary electrophoresis with laser-induced fluorescence detection for detailed studies on N-linked oligosaccharide profile of therapeutic recombinant monoclonal antibodies. (2006) Satoru Kamoda, Rika Ishikawa, Kazuaki Kakehi. Journal of Chromatography A, 1133, p332-339.
Profiling analysis of oligosaccharides in antibody pharmaceuticals by capillary electrophoresis. (2004) Satoru Kamoda, Chie Nomura, Mitsuhiro Kinoshita, Saori Nishiura, Rika Ishikawa, Kazuaki Kakehi,, Nana Kawasaki, Takao Hayakawa. Journal of Chromatography A, 1050, p211-216.
Capillary electrophoresis fingerprinting, quantification and mass-identification of various 9-aminopyrene-1,4,6-trisulfonate-derivatized oligomers derived from plant polysaccharides. (2006) Mirjam A. Kabel, Walter H. Heijnis, Edwin J. Bakx, Ren´e Kuijpers, Alphons G.J. Voragen, Henk A. Schols. Journal of Chromatography A, 1137, p119-126.
Capillary electrophoresis–mass spectrometry as a characterization tool for therapeutic proteins. (2006) LA Gennaro, O Salas-Solano, S Ma. Analytical Biochemistry, 355(2), p249-58.
Application of capillary zone electrophoresis and reversed-phase high-performance liquid chromatography in the biopharmaceutical industry for the quantitative analysis of the monosaccharides released from a highly glycosylated therapeutic protein. (2005) K Racaityte, S Kiessig, F Kalman. J Chromatography A, 1079, p354-365.
Capillary Electrophoresis of Carbohydrates Derivatized with Fluorophoric Compounds. S Ma, W Lau, RG Keck, JB Briggs, AJS Jones, K Moorhouse, W Nashabeh. a chapter in Methods in Molecular Biology. 308, p397-409.

Capillary Isoelectric Focusing (cIEF)
A systematic study in CIEF: Defining and optimizing experimental parameters critical to method reproducibility and robustness. Mack et al. Electrophoresis 2009, 30, 4049-4058 
The interstitial distribution of macromolecules in rat tumors is influenced by the negatively charged matrix components. (2005) H Wiig, CC Gyenge, and O Tenstad. J Physiol. 567 (2), p557-567.

BioSimilars
Determination of Somatropin Charged Variants by Capillary Zone Electrophoresis: Optimization, Verification, and Implementation of the European Pharmacopoeia Method. (2009) SM Storms, A Feltus, AR Barker, MA Joly, M Girard. Pharmeuropa Scientific Notes 2009-1.
Bacteriology
Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction 

Cancer Research
Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia by Schwartz et. al. Molecular and Cellular Endocrinology: Volume 320, Issues 1-2, 14 May 2010, Pages 76-86 
Gene expression-signature of belinostatin cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. Anne Monks et al. Anti-Cancer Drugs: September 2009 -Volume 20 -Issue 8 -pp 682-692
Effect of Ganodermaon drug-sensitive and multidrug-resistant small-cell lung carcinoma cells. D. Sadava, D. Still, R. Mudry, S. Kane. Cancer Letters 2009, Volume 277, Issue 2, Pages 182-189
Analytical validation of the GeXP analyzer and design of a workflow for cancer-biomarker discovery using multiplexed gene-expression profiling
Diagnosis of the Small Round Blue Cell Tumors Using Multiplex Polymerase Chain Reaction

Copy Number Variation and Allele Burden Analysis
JAK2V617F allele burden discriminates essential thrombocythemia from a subset of prefibrotic-stage primary myelofibrosis. Kais Hussein et al. Experimental Hematology 2009; 37: 1186-1193
Identification and characterisation of a large Senataxin (SETX) gene duplication in ataxia with ocular apraxia type 2 (AOA2)

Neuroscience
Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene 

Plant Biology
Genetic Variation for Lettuce Seed Thermoinhibition Is Associated with Temperature-sensitive Expression of Abscisic Acid, Gibberellin and Ethylene Biosynthesis, Metabolism and Response Genes
Involvement of the MADS-Box Gene ZMM4 in Floral Induction and Inflorescence Development in Maize
Highly Specific Gene Silencing by Artificial miRNAs in Rice
Veinal Necrosis Induced by Turnip mosaic virus Infection in Arabidopsis Is a Form of Defense Response Accompanying HR-Like Cell Death
FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis

Stem Cells
Obtaining Pluripotency Biomarker Signatures, Multiplex Gene-Expression Assay for Human Induced Pluripotent Stem Cells. Kathryn Sciabica, Ph.D., Knut Woltjen, Ph.D., Akitsu Hotta, Ph.D. 

Toxicology and Pharmaceutical Research
Nigellasativathymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemicrats. Maznah Ismail, Ghanya Al-Naqeepaand Kim Wei Chan. Free Radical Biology and Medicine. doi:10.1016/j.freeradbiomed.2009.12.002
Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector 
Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids
B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates
Gene Expression Analysis of Troglitazone Reveals its Impact on Multiple Pathways in Cell Culture: A Case for in vitro Platforms Combined With Gene Expression Analysis for Early (Idiosyncratic) Toxicity Screening

Virology
Detection of pandemic influenza A H1N1 virus by multiplex reverse transcription-PCR with a GeXP analyzer. Meng Qina et al. Journal of Virological Methods: 168 ( May 2010) 255-258
Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid
Rapid and sensitive detection of 68 unique varicella zoster virus gene transcripts in five multiplex reverse transcription-polymerase chain reactions

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